What every parent should understand before considering GLP-1 weight loss drugs for their child — and what the evidence points to instead.
In this episode of Pediatric Perspectives, I'm joined by integrative pediatrician Michelle Perro, M.D. — a clinician with 43 years of experience, an environmental medicine specialist, and the CEO and founder of GMO Science. Dr. Perro has spent decades studying how food, pesticides, and environmental toxicants affect children's health, and in this conversation she brings that perspective directly to bear on one of the most pressing issues in pediatrics today: childhood obesity and the growing push to treat it with GLP-1 agonist drugs.
In this episode, we cover:
- The scale of childhood obesity in the U.S. — and why Dr. Perro believes ultra-processed foods, GMOs, and pesticides are the primary drivers, not simply lifestyle choices
- What GLP-1 hormones are and how GLP-1 agonist drugs work — and why they look promising on paper but raise serious questions when used in children who are still growing
- The specific concerns Dr. Perro has identified: no long-term pediatric data, significant muscle loss, full weight rebound upon stopping, and side effects including gastroparesis, pancreatitis, and a black box warning for depression and suicidal ideation
- Why every class of pesticide she has reviewed functions as an endocrine disruptor — and what that has to do with the obesity epidemic
- Practical steps families can take right now, including how to shop, how to cook, and how to support children's microbiomes in ways that sustain healthy weight naturally
