With the Wind with Dr. Paul – Show 193: Pediatric Perspectives: Biopharmaceutical Debacle: How COVID Still Haunts Us with Peter McCullough, M.D.

In this episode of With the Wind: Science Revealed, Dr. Paul welcomes Dr. Peter McCullough, a highly published internist, cardiologist, and epidemiologist recognized for his early leadership during the COVID-19 pandemic. Their conversation focuses on early outpatient treatment, the lack of leadership from major medical institutions, concerns about the COVID-19 vaccine program, and new insights into spike protein persistence. This episode presents a clear and detailed look at what the data and clinical experience have shown.

When Institutions Withdrew, Early Treatment Emerged Elsewhere
Dr. Paul highlights Dr. McCullough’s landmark 2020 paper, Pathophysiological Basis and Rationale for Early Outpatient Treatment of SARS-CoV-2, which laid out the first organized outpatient treatment protocol in the early months of the pandemic. Dr. McCullough recounts his surprise that no major academic center—Harvard, Mayo Clinic, Cleveland Clinic, or others—ever produced such a protocol or positioned itself as a leader in early treatment. Hospitals instead waited for NIH and IDSA guidance, which focused solely on inpatient care rather than preventing hospitalization and death.

Real-World Observations and Outcomes
Dr. McCullough describes treating thousands of COVID patients, noting that the pulmonary exam in COVID differs from pneumonia or heart failure. He explains that many infectious disease doctors never examined COVID patients directly because of remote workflows. Published comparisons from the Dallas–Fort Worth area show that the McCullough Protocol was associated with an 85 percent reduction in hospitalization and death. He adds that the principles of the protocol have been attributed to saving tens of millions of lives and preventing hundreds of millions of hospitalizations.

Natural Immunity and Changing Disease Severity
According to Dr. McCullough, approximately 97 percent of people have had COVID based on national estimates and clinical antibody testing. Natural immunity is widespread, and the virus has mutated to a milder form. For most people, early treatment is no longer needed, though rare severe cases can still occur among the severely immunocompromised.

Reassessing the COVID-19 Vaccine Program
Dr. Paul references Cleveland Clinic findings showing an increased likelihood of COVID infection with more vaccine doses. Dr. McCullough notes that the 97 percent immunity rate results from widespread infection, not vaccination. He reiterates a position he first published in 2020: that the COVID-19 vaccine rollout represents the largest biopharmaceutical debacle in human history. He also discusses Pfizer’s early post-market data documenting 1,223 deaths within the first 90 days and asserts that both Pfizer and the FDA attempted to withhold this information.

The Childhood Vaccine Schedule Concern
Both doctors raise significant concerns about the CDC’s ACIP decision to add COVID-19 vaccines to the childhood schedule. They discuss that children rarely experienced severe COVID disease, that current boosters for children remain under emergency use authorization, and that serious concerns exist regarding cardiac, neurologic, immunologic, and thrombotic risks. Dr. Paul states that for children, the vaccine is “basically all harm and no benefit.” Dr. McCullough adds that hundreds of children have died following vaccination and emphasizes that even one death from a vaccine would be unacceptable. He also points out that no country in the world has removed COVID-19 vaccines from the market or schedule.

Spike Protein Engineering and Long-Term Persistence
Dr. McCullough explains that U.S. intelligence agencies agree that the virus was engineered in the Wuhan Institute of Virology. He describes how the spike protein docks with ACE2 and TMPRSS2 receptors, and references research showing the S1 segment can persist in the body for at least a year and a half following natural infection. These findings raise ongoing questions about long-term biological effects.

​This episode provides a detailed account of early COVID-19 treatment efforts, institutional gaps in response, concerns surrounding the vaccine program, and emerging insights into the nature and persistence of spike protein. Dr. McCullough’s firsthand clinical experience and research perspective offer clarity on decisions that shaped the last five years and the implications that remain today.